How does one release karma and change karmic conditioning?
Karma is action. You can release karma by going through the action or behavior until the original impetus of the karma is complete, or you can go to the source of action, in silence of pure consciousness and modify the karma. By transcending thought and action in meditation, we go beyond the conditioning of our past to create a better present. It is like rewriting our programming.
The purpose of all karma is to help bring us the experience and understanding of our true self based on our previous actions. When we experience our essential nature during meditation, we are getting this knowledge of the Self directly and so it satisfies the primary purpose of karma. That is why we can change karma through meditation.
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